Giant cell tumors are rare neoplasms, representing less than 5 % of all bone tumors. The vast majority of giant cell tumors occurs in extremity sites and is treated by surgery alone. However, a small percentage occurs in pelvis, spine or skull bones, where complete resection is challenging. Radiation therapy seems to be an option in these patients, despite the lack of a generally accepted dose or fractionation concept. Here we present a series of five cases treated with high dose IMRT. Patients and Methods From 2000 and 2006 a total of five patients with histologically proven benign giant cell tumors have been treated with IMRT in our institution.
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02/26/10